Monday, March 4, 2013

Today is 20th anniversary of Jim Valvano's famous "Don't Ever Give Up" speech


March 4th commemorates the 20th anniversary of Jim Valvano's memorable ESPY speech in which he announced that with ESPN, he would be forming The V Foundation for Cancer Research.

The Foundation kick-offs its 20 year anniversary this year and the money it has funded through donations have helped enormously in the battle against cancer that Dick Vitale has spearheaded.
The V Foundation has contributed to the fight against cancer with made many grants and donations. One significant example is a recent breakthrough by Dr. Reuben Harris and Dr. Douglass Yee of the University of Minnesota Masonic Cancer Center.

Their work with others over the years has led to the discovery of an enzyme that is believed to be the probable source of many genetic mutations in breast cancer. If scientists can find a way to block this enzyme, it may slow or stop the cancer from growling, researchers say.
The discovery, reported last month in the prestigious journal Nature, could pave the way for better ways of diagnosing and treating the disease, said Harris, who led the research.

The researchers found an enzyme called APOBEC3B that they say is the "probable source" of DNA mutations that are found in the majority of breast cancer cases.
"Mutations cause cancer. The enzyme appears to act like a 'genetic fuel,' causing cells to mutate and turn cancerous,” Harris said in announcing his findings to media outlets.

f an enzyme (A3B for short) that is the probable source of many genetic mutations in breast cancer. If scientists can find a way to block this enzyme, it may slow or stop

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